Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | BCR | P11274 | 2/20 | 0.55 |
| ▸ | PRKCA | P17252 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | SYK | P43405 | 11/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465915 | 0.88 | ABL1 (0.71) | ABL1BCRPRKCAPDGFRBSRC | |
| SCHEMBL7462511 | 0.82 | IKBKB (0.64) | ABL1BCRPRKCAPDGFRBSRC | |
| SCHEMBL7464672 | 0.81 | ABL1 (0.79) | ABL1BCRPRKCAPDGFRBSRC | |
| SCHEMBL7470857 | 0.79 | ABL1 (0.63) | ABL1BCRPRKCAPRKCDSYK | |
| SCHEMBL7535607 | 0.79 | SYK (0.54) | ABL1BCRPRKCAPDGFRBSRC | |
| SCHEMBL4903199 | 0.79 | IKBKB (0.64) | ABL1BCRPRKCAPDGFRBSRC | |
| SCHEMBL4902560 | 0.79 | ABL1 (0.72) | ABL1BCRPRKCAPDGFRBSRC | |
| SCHEMBL7464407 | 0.77 | SYK (0.59) | ABL1BCRPRKCASYK | |
| SCHEMBL4894535 | 0.77 | SYK (0.62) | ABL1BCRPRKCASYKIKBKB | |
| Hydrochloric Acid SCHEMBL10769093 | 0.76 | SYK (0.60) | ABL1BCRPRKCASYKIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |