SCHEMBL7536216

SCHEMBL7536216

CC=CC=C(C(=O)O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.42
GRIK2 Q13002 1/20 0.42
TRPA1 O75762 1/20 0.33
MAPK1 P28482 1/20 0.33
PTGS1 P23219 1/20 0.31
ALDH1A1 P00352 1/20 0.30
EP300 Q09472 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7536213 1.00 GRIK1 (0.42) GRIK1GRIK2TRPA1MAPK1PTGS1
SCHEMBL14607966 0.89 GRIK1 (0.39) GRIK1GRIK2TRPA1MAPK1
SCHEMBL7014840 0.87 GRIK1 (0.38) GRIK1GRIK2
SCHEMBL7014845 0.87 GRIK1 (0.38) GRIK1GRIK2
SCHEMBL24532073 0.81 GRIK1 (0.38) GRIK1GRIK2
SCHEMBL29036630 0.78
SCHEMBL19089794 0.78 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL14562262 0.78 ALDH1A1 (0.31) GRIK1GRIK2ALDH1A1
SCHEMBL13126254 0.78 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL18500782 0.78 GRIK1 (0.40) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US claimed
US-7795529-B2 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device MITSUBISHI PAPER MILLS LTD. (JP) 2010-09-14 US disclosed
US-7615640-B2 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device Mitsubishi PaperMillsLtd. (JP) 2009-11-10 US disclosed
US-20080149175-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device HORIUCHI TAMOTSU 2008-06-26 US disclosed
US-20080087327-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device HORIUCHI TAMOTSU 2008-04-17 US disclosed
EP-0849636-B1 Photosensitive polymer composition containing photosensitive polyamide and negative working photosensitive element KODAK POLYCHROME GRAPHICS CO (US) 2002-04-10 EP disclosed
US-6270945-B1 BLEND OF PHOTOPOLYMERIZABLE POLYMER AND DYE KODAK POLYCHROME GRAPHICS, LLC 2001-08-07 US disclosed
US-5962189-A Photosensitive composition containing photosensitive polyamide and thiazoline photoinitiator and negative working photosensitive element KODAK POLYCHROME GRAPHICS LLC (US) 1999-10-05 US disclosed
US-5925498-A Photosensitive polymer composition and element containing photosensitive polyamide and mixture of acrylates KODAK POLYCHROME GRAPHICS LLC (US) 1999-07-20 US disclosed
US-5879858-A COMPOSITION COMPRISING RESIN CONTAINING UNSATURATED PHOTOCROSSLINKABLE GROUPS, PHOTOPOLYMERIZABLE MONOMER, PHOTOCROSSLINKABLE POLYESTER RESIN, PHOTOINITIATOR KODAK POLYCHROME GRAPHICS, LLC (US) 1999-03-09 US disclosed
US-4647346-A IMPROVED ABRASION RESISTANCE EASTMAN KODAK COMPANY (US) 1987-03-03 US disclosed
US-4640886-A ANODIZED, SILICATED ALUMINUM SUPPORT, RADIATION SENSITIVE POLYESTER, BENZOIC ACID LAYERS TO IMPROVE INCUBATION STABILITY EASTMAN KODAK COMPANY (US) 1987-02-03 US disclosed
EP-0199467-A1 Polyesters comprising recurring photoconductive and photocrosslinkable units and elements thereof EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-10-29 EP disclosed
US-4609606-A LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1986-09-02 US disclosed
EP-0070898-B1 IMAGE-FORMING COMPOSITIONS CONTAINING PIGMENTS AND IONIC POLYESTER DISPERSING AGENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-10-16 EP disclosed
US-4419437-A SULFONIMIDE-CONTAINING AROMATIC DICARBOXYLIC ACID EASTMAN KODAK COMPANY (US) 1983-12-06 US disclosed
EP-0070898-A4 IMAGE-FORMING COMPOSITIONS CONTAINING PIGMENTS AND IONIC POLYESTER DISPERSING AGENTS. EASTMAN KODAK CO (US) 1983-07-04 EP disclosed
EP-0070898-A1 IMAGE-FORMING COMPOSITIONS CONTAINING PIGMENTS AND IONIC POLYESTER DISPERSING AGENTS. EASTMAN KODAK CO (US) 1983-02-09 EP disclosed
WO-1982002780-A1 IMAGE-FORMING COMPOSITIONS CONTAINING PIGMENTS AND IONIC POLYESTER DISPERSING AGENTS EASTMAN KODAK CO (US) 1982-08-19 WO disclosed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080149175-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device FTO, PPOX, CDH1 GRIK1 1773/4885GRIK2 1550/4885TRPA1 355/4885
US-20080087327-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device FTO, PPOX, CDH1 GRIK1 1773/4885GRIK2 1550/4885TRPA1 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.