SCHEMBL7536330

SCHEMBL7536330

O=Cc1ccc(Oc2c(C(=O)O)cc(C=O)c3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 2/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 2/20 0.40
MCL1 Q07820 1/20 0.40
DHODH Q02127 5/20 0.40
PARP10 Q53GL7 1/20 0.40
PARP3 Q9Y6F1 1/20 0.40
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.37
TTR P02766 1/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538596 0.82 WDR5 (0.47) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL7535252 0.82 MCL1 (0.43) ALDH1A1MAPTKDM4ERAB9AKMT2A
SCHEMBL7541958 0.80 MCL1 (0.41) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL9978740 0.79 MCL1 (0.60) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL7536335 0.78 SRD5A2 (0.46) PKMDHODHPARP10POLBTTR
SCHEMBL707315 0.72 CTNNB1 (0.53) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL7535711 0.71 THRB (0.54) ALDH1A1MAPTKDM4EKMT2AMCL1
SCHEMBL7191129 0.71 HSD17B10 (0.44) ALDH1A1MAPTKDM4EPKMKMT2A
SCHEMBL7535858 0.69 CDC25B (0.44) KDM4ERAB9ANPC1PKMKMT2A
SCHEMBL7537752 0.69 TTR (0.50) ALDH1A1MAPTKDM4ERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 ALDH1A1 1488/4885MAPT 3240/4885KDM4E 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.