SCHEMBL7541958

SCHEMBL7541958

O=Cc1ccc(Oc2c(C(=O)O)cc(C=O)c3ccccc23)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
ERN1 O75460 2/20 0.37
CDC25B P30305 2/20 0.37
KDM4E B2RXH2 4/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDE10A Q9Y233 1/20 0.36
NR4A1 P22736 1/20 0.36
NR4A2 P43354 1/20 0.36
NR4A3 Q92570 1/20 0.36
ABCB1 P08183 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
HPGD P15428 1/20 0.35
DHODH Q02127 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7543553 0.83 CDC25B (0.43) MCL1ALDH1A1MEN1MAPTKMT2A
SCHEMBL7537966 0.81 MCL1 (0.44) MCL1MEN1KMT2AERN1KDM4E
SCHEMBL7539694 0.80 CDC25B (0.46) ALDH1A1MEN1MAPTKMT2ACDC25B
SCHEMBL9978740 0.80 MCL1 (0.60) MCL1ALDH1A1MEN1MAPTKMT2A
SCHEMBL7536330 0.80 ALDH1A1 (0.45) MCL1ALDH1A1MAPTKMT2AKDM4E
SCHEMBL7537740 0.75 THRB (0.54) MCL1MEN1MAPTKMT2ACDC25B
SCHEMBL3267768 0.74 LMNA (0.61) ALDH1A1MEN1MAPTKMT2AERN1
SCHEMBL29957209 0.73 NR4A1 (0.48) ALDH1A1MEN1KMT2ACDC25BKDM4E
SCHEMBL2649947 0.73 NR4A1 (0.48) ALDH1A1MEN1KMT2ACDC25BKDM4E
SCHEMBL7535693 0.72 NPSR1 (0.42) MCL1ALDH1A1MAPTKMT2AERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 MCL1 3029/4885ALDH1A1 1488/4885MEN1 3828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.