Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.64 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669931 | 1.00 | DRD2 (0.64) | DRD2HTR1ADRD4DRD3HTR2A | |
| SCHEMBL12304200 | 0.80 | DRD2 (0.66) | DRD2HTR1ADRD4DRD3HTR2A | |
| SCHEMBL11820623 | 0.80 | HTR1A (0.66) | DRD2HTR1ADRD4DRD3HTR2A | |
| SCHEMBL7693542 | 0.79 | DRD2 (0.70) | DRD2HTR1ADRD4DRD3HTR2A | |
| Fumaric Acid SCHEMBL7989873 | 0.79 | HTR1A (0.67) | DRD2HTR1ADRD4DRD3MEN1 | |
| SCHEMBL28972657 | 0.78 | DRD2 (1.00) | DRD2HTR1ADRD4DRD3HTR2A | |
| SCHEMBL30547268 | 0.78 | RECQL (0.68) | DRD2HTR1ADRD3HTR2AMEN1 | |
| SCHEMBL11626341 | 0.78 | RECQL (0.68) | DRD2HTR1ADRD3HTR2AMEN1 | |
| SCHEMBL7542132 | 0.78 | DRD2 (0.62) | DRD2HTR1ADRD4DRD3HTR2A | |
| SCHEMBL7537267 | 0.78 | DRD2 (0.62) | DRD2HTR1ADRD4DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538154-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | claimed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | claimed |
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-31 | — | — | US | disclosed |
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | TPH1, HTR1A, HTR1E | DRD2 43/4885HTR1A 2/4885DRD4 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.