SCHEMBL160051

SCHEMBL160051

O=C(O)c1[c]cccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
ALOX15 P16050 2/20 0.50
KDM4E B2RXH2 4/20 0.43
HPGD P15428 2/20 0.43
NAPRT Q6XQN6 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MAPT P10636 3/20 0.41
HDAC8 Q9BY41 1/20 0.41
AKR1C3 P42330 2/20 0.40
POLB P06746 1/20 0.40
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28861029 0.96 ALDH1A1 (0.46) ALDH1A1ALOX15KDM4EHPGDNAPRT
Water SCHEMBL23706365 0.96 ALDH1A1 (0.46) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL3844824 0.77 ALDH1A1 (0.50) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL1191220 0.77 CA2 (0.44) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL753675 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL3727873 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL1180896 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL3093108 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL1181085 0.76 ALDH1A1 (0.50) ALDH1A1ALOX15KDM4EHPGDNAPRT
SCHEMBL1181086 0.76 ALDH1A1 (0.45) ALDH1A1ALOX15KDM4ESMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
EP-3715404-B1 POLYIMIDE FILM FOR DISPLAY SUBSTRATE LG CHEMICAL LTD (KR) 2024-04-10 EP claimed
CN-115275290-A Polybenzimidazole gel type high-temperature proton exchange membrane with functional/branched structure and preparation method thereof 浙江工业大学 2022-11-01 CN claimed
CN-111607053-B Thermoplastic polyurethane and molded article thereof 三晃股份有限公司 2022-06-07 CN claimed
US-20220153713-A1 HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) 2022-05-19 US claimed
US-20220153688-A1 HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) 2022-05-19 US claimed
EP-3992184-A1 HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS Shenzhen Cell Inspire Pharmaceutical Development Co., Ltd. (CN) 2022-05-04 EP claimed
EP-3992185-A1 HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA Shenzhen Cell Inspire Pharmaceutical Development Co., Ltd. (CN) 2022-05-04 EP claimed
CN-113105411-A Hydrazone amide derivatives and pharmaceutical compositions 深圳市三启药物开发有限公司 2021-07-13 CN claimed
US-20210087326-A1 POLYESTER POLYOL, THERMOPLASTIC POLYURETHANE AND ARTICLE THEREOF SUNKO INK CO., LTD. (TW) 2021-03-25 US claimed
US-5374301-A Inks suitable for use in ink jet printing ZENECA LIMITED (GB) 1994-12-20 US claimed
WO-1994016021-A1 AZO COMPOUND ZENECA LIMITED (GB) 1994-07-21 WO claimed
US-5268459-A Anionic azo compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-07 US claimed
US-5262527-A Disazo dyes suitable for use in ink jet printing IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-11-16 US claimed
US-5189154-A Ink jet printing dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 US claimed
EP-0468647-A1 Anionic compounds ZENECA LIMITED (GB) 1992-01-29 EP claimed
EP-0468649-A1 Anionic compounds ZENECA LIMITED (GB) 1992-01-29 EP claimed
EP-0468648-A1 Anionic bis(hydroxynaphthylamino) disazo dyestuffs and use thereof for ink jet printing ZENECA LIMITED (GB) 1992-01-29 EP claimed
US-4248998-A COMPOUNDS USED AS PLASTICIZERS FOR POLYVINYL CHLORIDE; POLYMERS USED AS FIBERS, FILMS, MOLDED ARTICLES STANDARD OIL COMPANY (INDIANA) (US) 1981-02-03 US claimed
US-4028112-A MEROCYANINE DYE WITH OXAZOLE NUCLEUS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153688-A1 HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS SOST, HDAC5, PTH1R ALDH1A1 644/4885ALOX15 1854/4885KDM4E 527/4885
US-20220153713-A1 HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA FH, HDGF, HRH4 ALDH1A1 652/4885ALOX15 1512/4885KDM4E 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.