Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PPIA | P62937 | 1/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.54 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537998 | 0.92 | PGR (0.55) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7539025 | 0.92 | MEN1 (0.62) | LMNATSHRAVPR2GPR27MEN1 | |
| SCHEMBL7532539 | 0.90 | LMNA (0.53) | LMNAHPGDTSHRPPIAAVPR2 | |
| SCHEMBL7560628 | 0.90 | LMNA (0.63) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7538011 | 0.88 | LMNA (0.55) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7533017 | 0.87 | LMNA (0.53) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7534436 | 0.86 | LMNA (0.60) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7537988 | 0.84 | LMNA (0.61) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7533715 | 0.84 | LMNA (0.52) | LMNAHPGDTSHRAVPR2GPR27 | |
| SCHEMBL7537216 | 0.83 | ALDH1A1 (0.58) | LMNAHPGDTSHRAVPR2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |