Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537988 | 0.92 | LMNA (0.61) | LMNAHPGDTSHRGPR27AVPR2 | |
| SCHEMBL7560628 | 0.91 | LMNA (0.63) | LMNAHPGDTSHRGPR27AVPR2 | |
| SCHEMBL7538011 | 0.88 | LMNA (0.55) | LMNAHPGDTSHRGPR27AVPR2 | |
| SCHEMBL7537030 | 0.88 | MAPT (0.53) | LMNAHPGDGPR27KDM4ECYP1A2 | |
| SCHEMBL7539008 | 0.87 | LMNA (0.60) | LMNAHPGDTSHRGPR27AVPR2 | |
| SCHEMBL7537216 | 0.84 | ALDH1A1 (0.58) | LMNAHPGDTSHRGPR27AVPR2 | |
| SCHEMBL7531331 | 0.84 | DHODH (0.55) | LMNAHPGDTSHRKDM4ECYP3A4 | |
| SCHEMBL7562743 | 0.83 | ACLY (0.52) | GPR27AVPR2KMT2AMEN1GAA | |
| SCHEMBL7534436 | 0.81 | LMNA (0.60) | LMNAHPGDTSHRGPR27AVPR2 | |
| SCHEMBL7563545 | 0.81 | CCR2 (0.48) | LMNAHPGDKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |