Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.65 |
| ▸ | CTSB | P07858 | 13/20 | 0.65 |
| ▸ | CTSS | P25774 | 13/20 | 0.65 |
| ▸ | CTSK | P43235 | 13/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647901 | 0.92 | CTSL (0.65) | CTSLCTSBCTSSCTSKHDAC3 | |
| SCHEMBL7534190 | 0.81 | CTSK (0.91) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7537340 | 0.77 | CTSL (0.66) | CTSLCTSBCTSSCTSKHDAC3 | |
| SCHEMBL7537053 | 0.74 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7569060 | 0.73 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7647908 | 0.73 | CTSL (0.68) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7535316 | 0.73 | CTSL (0.40) | CTSLCTSBCTSSCTSKFAAH | |
| SCHEMBL7529726 | 0.72 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7531501 | 0.71 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7528461 | 0.71 | CTSL (0.62) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |