Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.65 |
| ▸ | CTSB | P07858 | 13/20 | 0.65 |
| ▸ | CTSS | P25774 | 13/20 | 0.65 |
| ▸ | CTSK | P43235 | 11/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537335 | 0.92 | CTSL (0.65) | CTSLCTSBCTSSCTSKHDAC3 | |
| SCHEMBL7537053 | 0.79 | CTSS (1.00) | CTSLCTSBCTSSCTSKKDM4E | |
| SCHEMBL7647908 | 0.78 | CTSL (0.68) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7537370 | 0.77 | POLB (0.40) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL7534190 | 0.76 | CTSK (0.91) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7569060 | 0.74 | CTSS (1.00) | CTSLCTSBCTSSCTSKABCG2 | |
| SCHEMBL7529726 | 0.72 | CTSS (1.00) | CTSLCTSBCTSSCTSKKDM4E | |
| SCHEMBL7535316 | 0.72 | CTSL (0.40) | CTSLCTSBCTSSCTSKKDM4E | |
| SCHEMBL7537340 | 0.71 | CTSL (0.66) | CTSLCTSBCTSSCTSKHDAC3 | |
| SCHEMBL7531501 | 0.69 | CTSS (1.00) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |