Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701691 | 0.80 | SIRT1 (0.60) | HTTKMT2AGAAMEN1HPGD | |
| Iodide SCHEMBL7710889 | 0.79 | SIRT1 (0.58) | HTTKMT2AGAAMEN1HPGD | |
| SCHEMBL515125 | 0.76 | HTT (0.51) | HTTKMT2AGAAMEN1HPGD | |
| SCHEMBL9669181 | 0.76 | HTT (0.55) | HTTKMT2AGAAMEN1HPGD | |
| SCHEMBL31620817 | 0.75 | ALDH1A1 (0.53) | HTTKMT2AGAAMEN1HPGD | |
| SCHEMBL4066790 | 0.75 | IRAK4 (0.39) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL4622473 | 0.75 | MAOA (0.46) | HTTKMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL709788 | 0.74 | POLB (0.68) | HTTKMT2AGAAMEN1HPGD | |
| SCHEMBL29391544 | 0.74 | POLB (0.68) | HTTKMT2AGAAMEN1HPGD | |
| SCHEMBL20824816 | 0.74 | HTT (0.44) | HTTKMT2AGAAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002034251-A1 | TREATMENT OF ASTHMA WITH LFM ANALOGUES | PARKER HUGHES INSTITUTE (US) | 2002-05-02 | — | — | WO | disclosed |