Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 7/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546168 | 0.93 | ITGB1 (0.54) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7540570 | 0.93 | ITGB1 (0.54) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7539261 | 0.86 | MMP3 (0.47) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7548271 | 0.86 | FOLH1 (0.51) | MMP3MMP2ITGB1ITGA4MAPT | |
| SCHEMBL7545100 | 0.85 | ITGB1 (0.51) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7543834 | 0.85 | MMP3 (0.46) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7543837 | 0.85 | MMP3 (0.46) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7540008 | 0.85 | MMP3 (0.50) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7545880 | 0.84 | FPR2 (0.55) | MMP3MMP2MMP1ITGB1ITGA4 | |
| SCHEMBL7547312 | 0.83 | MMP3 (0.44) | MMP3MMP2MMP1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |