SCHEMBL7538748

SCHEMBL7538748

CC(=O)NC(=O)c1ccc(C=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
EPHX2 P34913 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PARP10 Q53GL7 1/20 0.42
PARP3 Q9Y6F1 1/20 0.42
CYP2A6 P11509 1/20 0.41
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
GAA P10253 2/20 0.41
LMNA P02545 1/20 0.41
UBE2N P61088 1/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TBXAS1 P24557 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15482198 0.85 HDAC6 (0.52) ALDH1A1MEN1MAPTKMT2ATDP1
SCHEMBL944150 0.83 HDAC2 (0.59) ALDH1A1EPHX2NR1H4PARP10PARP3
SCHEMBL12522467 0.82 TAS1R3 (0.53) ALDH1A1MEN1MAPTKMT2ATDP1
SCHEMBL19435773 0.81 ALDH1A1 (0.52) ALDH1A1EPHX2NR1H4TDP1PARP10
SCHEMBL24212110 0.78 HDAC6 (0.53) ALDH1A1EPHX2NR1H4SMN1; SMN2HDAC6
SCHEMBL15358837 0.77 HDAC1 (0.64) ALDH1A1MEN1KMT2ALMNAHDAC6
SCHEMBL7537701 0.77 CYP3A4 (0.56) ALDH1A1NR1H4MEN1MAPTKMT2A
SCHEMBL13273398 0.77 ALDH1A1 (0.65) ALDH1A1MEN1MAPTKMT2ATDP1
SCHEMBL97268 0.76 ALDH1A1 (0.62) ALDH1A1MAPTKMT2APARP10PARP3
SCHEMBL11060500 0.75 SMN1; SMN2 (0.66) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 ALDH1A1 1488/4885EPHX2 582/4885NR1H4 3271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.