Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681528 | 0.84 | HDAC8 (0.57) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2HDAC2 | |
| SCHEMBL15482198 | 0.83 | HDAC6 (0.52) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL7538748 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL24799683 | 0.78 | ALDH1A1 (0.59) | TAS1R3TAS1R1ALDH1A1TDP1MEN1 | |
| SCHEMBL3809792 | 0.78 | HDAC1 (0.62) | TAS1R3TAS1R1ALDH1A1HDAC2HDAC6 | |
| SCHEMBL273504 | 0.77 | ALDH1A1 (0.52) | TAS1R3TAS1R1ALDH1A1TDP1MAPT | |
| SCHEMBL26429893 | 0.77 | TAS1R3 (0.45) | TAS1R3TAS1R1ALDH1A1TDP1MEN1 | |
| SCHEMBL9109998 | 0.76 | MPO (0.57) | TAS1R3TAS1R1ALDH1A1MAPTLMNA | |
| SCHEMBL2055312 | 0.76 | TAS1R3 (0.51) | TAS1R3TAS1R1ALDH1A1TDP1MAPT | |
| SCHEMBL22698733 | 0.76 | TAS1R3 (0.64) | TAS1R3TAS1R1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150321996-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2015-11-12 | — | — | US | disclosed |
| US-9066972-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20150094379-A1 | Dendrimer Compositions | GENZYME CORP (US) | 2015-04-02 | — | — | US | disclosed |
| US-20150011645-A1 | AMINE DENDRIMERS | GENZYME CORP (US) | 2015-01-08 | — | — | US | disclosed |
| US-8900560-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-8889738-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140235724-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |
| US-20130251667-A1 | AMIDE DENDRIMER COMPOSITIONS | SANOFI (FR) | 2013-09-26 | — | — | US | disclosed |
| US-8425887-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2010-07-01 | — | — | US | disclosed |
| US-20100129309-A1 | AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION | 2010-05-27 | — | — | US | disclosed |
| US-20100124542-A1 | AMINE DENDRIMERS | GENZYME CORPORATION (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100069500-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
| WO-2008133954-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008109095-A1 | SULFONE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008103368-A1 | AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008076242-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008042222-A2 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008027551-A2 | DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130251667-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | TAS1R3 482/4885TAS1R1 547/4885ALDH1A1 4513/4885 |
| US-20100124542-A1 | AMINE DENDRIMERS | PHOSPHO1, PHPT1, PPIP5K2 | TAS1R3 1297/4885TAS1R1 1592/4885ALDH1A1 4239/4885 |
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | PAM, PHOSPHO1, ARID2 | TAS1R3 263/4885TAS1R1 391/4885ALDH1A1 4797/4885 |
| US-20100129309-A1 | AMINE POLYMER COMPOSITIONS | PHPT1, PHOSPHO1, PTH1R | TAS1R3 1830/4885TAS1R1 1728/4885ALDH1A1 3775/4885 |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | PAM, ARGLU1, NAAA | TAS1R3 231/4885TAS1R1 351/4885ALDH1A1 4758/4885 |
| US-20140235724-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | TAS1R3 482/4885TAS1R1 547/4885ALDH1A1 4513/4885 |
| US-20150011645-A1 | AMINE DENDRIMERS | PHOSPHO1, PHPT1, PPIP5K2 | TAS1R3 1297/4885TAS1R1 1592/4885ALDH1A1 4239/4885 |
| US-20100069500-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | TAS1R3 482/4885TAS1R1 547/4885ALDH1A1 4513/4885 |
| US-20150321996-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | TAS1R3 482/4885TAS1R1 547/4885ALDH1A1 4513/4885 |
| US-20150094379-A1 | Dendrimer Compositions | PHPT1, HRH3, PHOSPHO1 | TAS1R3 1154/4885TAS1R1 1481/4885ALDH1A1 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.