Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537349 | 0.97 | LMNA (0.53) | LMNASMN1; SMN2MAPTTP53TDP1 | |
| SCHEMBL7533629 | 0.85 | LMNA (0.51) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL7533715 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2MAPTTP53TDP1 | |
| SCHEMBL7539018 | 0.84 | LMNA (0.49) | LMNASMN1; SMN2MAPTTDP1MEN1 | |
| SCHEMBL7533462 | 0.83 | MAPT (0.49) | LMNASMN1; SMN2MAPTTP53NPC1 | |
| SCHEMBL7537038 | 0.82 | HTT (0.51) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL7539012 | 0.82 | LMNA (0.47) | LMNASMN1; SMN2MAPTTP53TSHR | |
| SCHEMBL7539008 | 0.82 | LMNA (0.60) | LMNASMN1; SMN2MAPTTDP1MEN1 | |
| SCHEMBL7531331 | 0.81 | DHODH (0.55) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7560628 | 0.81 | LMNA (0.63) | LMNAMAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |