Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MOGAT2 | Q3SYC2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533462 | 0.97 | MAPT (0.49) | LMNASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL7537038 | 0.96 | HTT (0.51) | LMNASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL7539015 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL7530740 | 0.84 | MEN1 (0.50) | LMNASMN1; SMN2MAPTHTTTSHR | |
| SCHEMBL7535071 | 0.84 | LMNA (0.47) | LMNASMN1; SMN2MAPTHTTNPC1 | |
| SCHEMBL7537385 | 0.83 | ACLY (0.51) | LMNASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL7537349 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL7125249 | 0.83 | HTT (0.56) | LMNASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL7531158 | 0.82 | NPC1 (0.55) | SMN1; SMN2MAPTHTTNPC1PKM | |
| SCHEMBL7532791 | 0.81 | MEN1 (0.49) | LMNATP53MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |