Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537343 | 0.97 | S1PR3 (0.47) | LMNATSHRHPGDKAT6AACLY | |
| SCHEMBL7539018 | 0.90 | LMNA (0.49) | LMNATSHRHPGDKAT6AACLY | |
| SCHEMBL7537356 | 0.87 | LMNA (0.47) | LMNATSHRHPGDKAT6AACLY | |
| SCHEMBL7533711 | 0.84 | LMNA (0.49) | LMNATSHRHPGDKAT6AACLY | |
| SCHEMBL7539015 | 0.82 | LMNA (0.55) | LMNATSHRHPGDKAT6ASMN1; SMN2 | |
| SCHEMBL7537995 | 0.82 | ACLY (0.56) | LMNATSHRHPGDACLYPARP10 | |
| SCHEMBL7537349 | 0.80 | LMNA (0.53) | LMNATSHRHPGDKAT6ASMN1; SMN2 | |
| SCHEMBL7533705 | 0.79 | SCN3A (0.56) | LMNATSHRACLYSMN1; SMN2HTT | |
| SCHEMBL532975 | 0.78 | ACLY (0.69) | LMNATSHRHPGDACLYHTT | |
| Hydrochloric Acid SCHEMBL533067 | 0.77 | ACLY (0.68) | LMNATSHRHPGDACLYHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |