Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 6/20 | 0.48 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 11/20 | 0.48 |
| ▸ | MMP1 | P03956 | 9/20 | 0.47 |
| ▸ | MMP13 | P45452 | 6/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360559 | 0.85 | MMP13 (0.62) | MMP2ADAM17MMP14MMP8MMP9 | |
| SCHEMBL7998659 | 0.77 | MMP2 (0.57) | MMP2MMP9MMP1MMP13 | |
| SCHEMBL8002344 | 0.76 | MMP2 (0.51) | MMP2MMP8MMP9MMP1MMP13 | |
| SCHEMBL8002779 | 0.76 | MMP2 (0.51) | MMP2ADAM17MMP9MMP1MMP13 | |
| SCHEMBL7539103 | 0.76 | MMP2 (0.65) | MMP2MMP9MMP1 | |
| SCHEMBL7539094 | 0.76 | MMP2 (0.65) | MMP2MMP9MMP1 | |
| SCHEMBL7998743 | 0.74 | MMP2 (0.49) | MMP2ADAM17MMP14MMP8MMP9 | |
| SCHEMBL7990368 | 0.73 | MMP9 (0.54) | MMP2MMP14MMP8MMP9MMP1 | |
| SCHEMBL8002263 | 0.73 | MMP9 (0.55) | MMP2MMP14MMP8MMP9MMP1 | |
| SCHEMBL6740661 | 0.73 | TP53 (0.47) | MMP2TP53MMP9MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | disclosed |