SCHEMBL75403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24262284	0.86	SSTR4 (0.38)	SSTR4POLBALDH1A1KDM4E
	SCHEMBL3923944	0.84	POLB (0.46)	HCRTR2MTNR1ASSTR4LTB4RLTB4R2
	SCHEMBL3930074	0.84	POLB (0.46)	HCRTR2MTNR1ASSTR4LTB4RLTB4R2
	SCHEMBL76686	0.79	ALDH1A1 (0.40)	ALDH1A1
	SCHEMBL27594439	0.78	HCRTR2 (0.40)	HCRTR2SSTR4LTB4RLTB4R2CYP19A1
	SCHEMBL19719096	0.78	HTR2B (0.41)	HCRTR2MTNR1ASSTR4LTB4RLTB4R2
	SCHEMBL12216206	0.78	LTB4R (0.36)	HCRTR2SSTR4LTB4RLTB4R2CYP19A1
	SCHEMBL11964313	0.77	HSD17B3 (0.40)	POLBALDH1A1KDM4E
	SCHEMBL11870882	0.75	SSTR4 (0.38)	HCRTR2SSTR4LTB4RLTB4R2CYP19A1
	SCHEMBL25615385	0.75	LTB4R (0.39)	MTNR1ALTB4RLTB4R2CYP19A1GLS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.