Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 11/20 | 0.63 |
| ▸ | BMP1 | P13497 | 1/20 | 0.63 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.62 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729777 | 0.86 | TAS2R14 (0.80) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL6321588 | 0.84 | TAS2R14 (0.69) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL6324095 | 0.84 | TAS2R14 (0.65) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL7343981 | 0.82 | BMP1 (0.77) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL2445958 | 0.81 | TAS2R14 (0.82) | TAS2R14CXCR3PTGESTAS2R8CNR2 | |
| SCHEMBL5092519 | 0.79 | KEAP1 (0.81) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL9287153 | 0.79 | RORC (0.68) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL13900691 | 0.79 | TAS2R14 (0.65) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL6997496 | 0.78 | BMP1 (0.89) | TAS2R14BMP1CXCR3PTGESTAS2R8 | |
| SCHEMBL22265923 | 0.78 | ALDH1A1 (0.66) | TAS2R14BMP1CXCR3PTGESTAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939629-A4 | THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS | MONSANTO CO (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0939629-A1 | THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998003166-A1 | THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |