SCHEMBL5483965

SCHEMBL5483965

NNc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
MAPK1 P28482 1/20 0.48
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.44
CTSD P07339 1/20 0.43
SRC P12931 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
AOC3 Q16853 4/20 0.39
BCAT2 O15382 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
RECQL P46063 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4613678 0.89 LMNA (0.50) LMNACES2CES1MAPK1KDM4E
SCHEMBL7326944 0.86 LMNA (0.53) LMNACES2CES1MAPK1KDM4E
SCHEMBL1395462 0.84 LMNA (0.52) LMNACES2CES1MAPK1KDM4E
SCHEMBL2053138 0.84 LMNA (0.52) LMNACES2CES1MAPK1KDM4E
SCHEMBL754132 0.81 CYP2C19 (0.58) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL4769362 0.80 LMNA (0.47) LMNACES2CES1MAPK1KDM4E
SCHEMBL11667579 0.80 LMNA (0.47) LMNACES2CES1MAPK1KDM4E
Formic Acid SCHEMBL28872029 0.79 LMNA (0.46) LMNACES2CES1MAPK1KDM4E
SCHEMBL5928515 0.79 ALDH1A1 (0.62) LMNACES2CES1KDM4EALDH1A1
SCHEMBL5843726 0.79 MDM4 (0.53) LMNACES2CES1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104672332-B Antibody, ELISA method and kit for detecting free gossypol 武汉市畜牧兽医科学研究所 2018-10-09 CN disclosed
CN-104558176-B Monoclonal antibody and enzyme-linked immunoassay method and kit for detecting androgens medicine 华中农业大学 2017-09-01 CN disclosed
CN-104558171-B Monoclonal antibody and enzyme-linked immunoassay method and kit for detecting methyltestosterone 华中农业大学 2017-07-04 CN disclosed
CN-104672332-A Antibody for testing free gossypol, ELISA (enzyme-linked immune sorbent assay) method and kit WUHAN RES INST OF ANIMAL AND VETERINARY SCIENCE 2015-06-03 CN disclosed
CN-104558176-A Monoclonal antibody, enzyme-linked immunosorbent assay method and kit for detecting androgens UNIV HUAZHONG AGRICULTURAL 2015-04-29 CN disclosed
CN-104558171-A Monoclonal antibody, enzyme linked immunosorbent assay and kit for detecting methyltestosterone UNIV HUAZHONG AGRICULTURAL 2015-04-29 CN disclosed
CN-102617589-A Artificial antigen for aflatoxin M1 and antibody prepared by same UNIV CHINA AGRICULTURAL 2012-08-01 CN disclosed
CN-101105492-B Monoclonal antibody and enzyme-linked immunoassay method and reagent kit for detecting tylosin and tilmicosin residue UNIV HUAZHONG AGRICULTURAL 2011-05-04 CN disclosed
CN-101105492-A Monoclonal antibody and enzyme-linked immunoassay method and reagent kit for detecting tylosin and tilmicosin residue UNIV HUAZHONG AGRICULTURAL (CN) 2008-01-16 CN disclosed
US-20070258969-A1 Compositions and methods for targeting metastatic tumors using multivalent ligand-linked carbohydrate polymers GALECTIN THERAPEUTICS, INC. 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070258969-A1 Compositions and methods for targeting metastatic tumors using multivalent ligand-linked carbohydrate polymers CD44, ALG1, FUT6 LMNA 2062/4885CES2 2336/4885CES1 2251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.