SCHEMBL754148

SCHEMBL754148

CCOC(=O)c1nc[nH]n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
PDE4D Q08499 1/20 0.46
CYP1A2 P05177 1/20 0.43
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 2/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA7 P43166 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6849841 0.98 KDM4E (0.46) KDM4EPDE4DCYP1A2TSHRSMN1; SMN2
SCHEMBL8719104 0.98 KDM4E (0.46) KDM4EPDE4DCYP1A2TSHRSMN1; SMN2
SCHEMBL9248449 0.81 KDM4E (0.38) KDM4EPDE4DTSHRSMN1; SMN2KMT2A
SCHEMBL22372048 0.80 TSHR (0.47) KDM4ETSHRSMN1; SMN2GAALMNA
SCHEMBL22372041 0.78 PHLPP2 (0.46) KDM4ECYP1A2SMN1; SMN2ALDH1A1GAA
SCHEMBL9066023 0.77 CYP3A4 (0.47) KDM4ETSHRKMT2AMEN1ALDH1A1
SCHEMBL8115353 0.76 CA12 (0.53) KDM4ECYP1A2SMN1; SMN2KMT2AMEN1
SCHEMBL22372261 0.75 JMJD6 (0.39)
SCHEMBL30990056 0.75 PDE4D (0.45) KDM4EPDE4DCYP1A2KMT2AMEN1
SCHEMBL489524 0.74 TSHR (0.52) KDM4ECYP1A2TSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12612396-B1 Modulators of beta catenin and uses thereof DEWPOINT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
US-12264138-B2 Process for the preparation of microbiocidal oxadiazole derivatives SYNGENTA CROP PROTECTION AG (CH) 2025-04-01 US disclosed
US-20250059185-A1 BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2025-02-20 US disclosed
EP-4448522-A1 BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS F. Hoffmann-La Roche AG (CH) 2024-10-23 EP disclosed
CN-118541458-A Polishing liquid for CMP, storage liquid and polishing method 株式会社力森诺科 2024-08-23 CN disclosed
CN-118488953-A Bicyclic heterocyclic compounds useful as monoacylglycerol lipase inhibitors 豪夫迈·罗氏有限公司 2024-08-13 CN disclosed
US-20240254119-A1 COMPOUNDS AND COMPOSITIONS AS c-Kit KINASE INHIBITORS Calixis Inc. 2024-08-01 US disclosed
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed
US-5744597-A Stereoselective anion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides ELI LILLY AND COMPANY (US) 1998-04-28 US disclosed
EP-0577303-B1 Stereoselective glycosylation process LILLY CO ELI (US) 1997-10-01 EP disclosed
EP-0577304-B1 Stereoselective anion glycosylation process LILLY CO ELI (US) 1997-03-05 EP disclosed
CN-1085560-A Stereoselective glycosylation process LILLY CO ELI (US) 1994-04-20 CN disclosed
EP-0577304-A1 Stereoselective anion glycosylation process ELI LILLY AND COMPANY (US) 1994-01-05 EP disclosed
EP-0577303-A1 Stereoselective glycosylation process ELI LILLY AND COMPANY (US) 1994-01-05 EP disclosed
US-5144027-A Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates TOYAMA CHEMICAL CO., LTD. (JP) 1992-09-01 US disclosed
US-4879381-A ANTIBIOTICS TOYOMA CHEMICAL COMPANY, LTD. (JP) 1989-11-07 US disclosed
US-4673738-A Novel intermediates of cephalosporins and process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl-Δ3 -cephem-4-carboxylic acids HANDI-PAC INC. (US) 1987-06-16 US disclosed
US-4489072-A BACTERICIDE, ANTIBIOTIC TOYAMA CHEMICAL CO., LTD. (JP) 1984-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612396-B1 Modulators of beta catenin and uses thereof CTNNB1, CTNND1, CTNNA1 KDM4E 3895/4885PDE4D 2277/4885CYP1A2 4550/4885
US-20250059185-A1 BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS MGLL, LIPC, PNLIP KDM4E 2738/4885PDE4D 1758/4885CYP1A2 464/4885
US-12264138-B2 Process for the preparation of microbiocidal oxadiazole derivatives CYP51A1, MPO, NOX5 KDM4E 2124/4885PDE4D 463/4885CYP1A2 30/4885
US-20240254119-A1 COMPOUNDS AND COMPOSITIONS AS c-Kit KINASE INHIBITORS KIT, AURKC, PRKCE KDM4E 719/4885PDE4D 931/4885CYP1A2 4125/4885
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF CTNNB1, CTNND1, CTNNA1 KDM4E 3895/4885PDE4D 2277/4885CYP1A2 4550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.