Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547636 | 0.92 | DRD2 (0.46) | DRD2HTR2ACEPT1GSTP1MAPT | |
| SCHEMBL7542077 | 0.91 | CEPT1 (0.42) | DRD2HTR2ACEPT1GSTP1MAPT | |
| SCHEMBL7544004 | 0.90 | MAPT (0.46) | MAPTLMNATP53POLBALOX5 | |
| SCHEMBL7542425 | 0.86 | ALOX5 (0.48) | MAPTLMNATP53POLBALOX5 | |
| SCHEMBL7541433 | 0.86 | MAPT (0.46) | MAPTLMNATP53POLBPIK3CA | |
| SCHEMBL7542942 | 0.83 | AGPAT2 (0.43) | CEPT1MAPTLMNATP53ALOX5 | |
| SCHEMBL7545106 | 0.83 | CEPT1 (0.42) | CEPT1MAPTLMNATP53ALOX5 | |
| SCHEMBL7549421 | 0.83 | MAPK13 (0.41) | DRD2HTR2AGSTP1MAPTPOLB | |
| SCHEMBL7548836 | 0.82 | MAPT (0.46) | CEPT1MAPTLMNATP53KDR | |
| SCHEMBL7541140 | 0.82 | LMNA (0.53) | MAPTLMNAPOLBALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |