Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541805 | 1.00 | PPARA (0.57) | PPARAPPARGKYNUCASP3FNTA | |
| SCHEMBL7546272 | 0.90 | FNTA (0.53) | PPARAPPARGKYNUCASP3FNTA | |
| SCHEMBL7546269 | 0.90 | FNTA (0.53) | PPARAPPARGKYNUCASP3FNTA | |
| SCHEMBL23961328 | 0.84 | KYNU (0.62) | PPARAPPARGKYNUALDH1A1ALOX15 | |
| SCHEMBL30417364 | 0.83 | KYNU (0.60) | PPARAPPARGKYNUALDH1A1ALOX15 | |
| SCHEMBL7545004 | 0.83 | ITGA4 (0.47) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7545015 | 0.83 | ITGA4 (0.47) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL23927277 | 0.82 | PPARA (0.73) | PPARAPPARGALDH1A1ALOX15CASP1 | |
| SCHEMBL24106058 | 0.82 | CASP3 (0.56) | KYNUCASP3ALDH1A1ALOX15CASP1 | |
| SCHEMBL7542832 | 0.81 | PPARA (0.65) | PPARAPPARGKYNUALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |