Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549200 | 0.89 | REV1 (0.49) | MGAMGAASIMGAM2REV1 | |
| SCHEMBL7539595 | 0.86 | MAOB (0.47) | PDGFRBPDGFRAMGAMGAASI | |
| SCHEMBL5387585 | 0.83 | ALOX5 (0.49) | ALOX5P2RY14MAOBGSTP1NPC1 | |
| SCHEMBL5382479 | 0.82 | P2RY14 (0.47) | ALOX5P2RY14MAOBGSTP1PTPN1 | |
| SCHEMBL5379303 | 0.82 | ALOX5 (0.48) | ALOX5P2RY14MAOBGSTP1NPC1 | |
| SCHEMBL6595113 | 0.78 | PTGER3 (0.61) | ALOX5GAAP2RY14GSTP1 | |
| SCHEMBL6595111 | 0.78 | PTGER3 (0.61) | ALOX5GAAP2RY14GSTP1 | |
| SCHEMBL28080889 | 0.77 | GSTP1 (0.55) | GAAMAOBGSTP1NPC1RAB9A | |
| SCHEMBL5385300 | 0.77 | LTB4R (0.47) | ALOX5P2RY14 | |
| SCHEMBL5385296 | 0.76 | PTGER3 (0.48) | ALOX5P2RY14MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |