SCHEMBL754226

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13351851	0.87	LMNA (0.47)	LMNATP53MAPTMEN1KMT2A
	SCHEMBL753165	0.78	TNKS (0.53)	LMNATP53KMT2ACYP3A4ALDH1A1
	SCHEMBL30807193	0.72	CYP3A4 (0.77)	NMUR2LMNATP53MAPTMEN1
	SCHEMBL753035	0.70	NMUR2 (0.50)	NMUR2LMNATP53MAPTMEN1
	SCHEMBL2578582	0.70	HDAC1 (0.64)	LMNAMAPTALDH1A1HPGDHDAC1
	SCHEMBL753195	0.69	BRD4 (0.39)	LMNAMEN1KMT2AABCB1RXFP1
	SCHEMBL752464	0.65	ALDH1A1 (0.52)	NMUR2LMNATP53MAPTMEN1
	SCHEMBL2746872	0.65	MEN1 (0.90)	NMUR2LMNATP53MAPTMEN1
	SCHEMBL30807185	0.64	KDM4E (0.74)	NMUR2LMNATP53MAPTMEN1
	SCHEMBL345696	0.64	MEN1 (1.00)	NMUR2LMNATP53MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.