SCHEMBL752464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756396	0.83	LMNA (0.56)	ALDH1A1SMN1; SMN2TP53MAPTKMT2A
	SCHEMBL16925485	0.81	SMN1; SMN2 (0.48)	ALDH1A1SMN1; SMN2TP53MAPTRXFP1
	SCHEMBL755830	0.77	MAPT (0.43)	ALDH1A1TP53MAPTKMT2AMEN1
	SCHEMBL765013	0.74	NPC1 (0.42)	ALDH1A1SMN1; SMN2TP53MAPTKMT2A
	SCHEMBL13351798	0.74	NMUR2 (0.41)	ALDH1A1SMN1; SMN2TP53MAPTKMT2A
	SCHEMBL14260035	0.73	MMP3 (0.81)	ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
	SCHEMBL752884	0.72	KDM4E (0.65)	ALDH1A1SMN1; SMN2TP53MAPTKMT2A
	SCHEMBL30224972	0.70	CYP3A4 (0.54)	ALDH1A1SMN1; SMN2TP53MAPTKMT2A
	SCHEMBL12697363	0.70	KMT2A (0.71)	ALDH1A1SMN1; SMN2MAPTKMT2ALMNA
	SCHEMBL30706498	0.70	MAOB (0.81)	ALDH1A1KMT2AKDM4EHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.