Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543301 | 0.81 | GABRG2 (0.43) | ALDH1A1SMN1; SMN2LMNAKMT2AELANE | |
| SCHEMBL7708926 | 0.78 | TSHR (0.41) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL5551223 | 0.77 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL5551219 | 0.77 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL7377685 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2MITFKCNJ1KCNH2 | |
| SCHEMBL13088391 | 0.76 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MITFKCNJ1KCNH2 | |
| SCHEMBL15486702 | 0.71 | ALDH1A1 (0.65) | ALDH1A1LMNAKMT2A | |
| SCHEMBL7547077 | 0.70 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL30552529 | 0.69 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL15486296 | 0.68 | NPC1 (0.77) | ALDH1A1SMN1; SMN2MITFLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211239-A1 | PROCESS FOR THE PREPARATION OF 2,3-DIHYDROAZEPINE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2002-06-05 | — | — | EP | disclosed |