SCHEMBL7543481

SCHEMBL7543481

c1ccc(Oc2ccc(OCCOc3ccccn3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.55
PLA2G2A P14555 1/20 0.55
PTGS2 P35354 1/20 0.54
KCNA3 P22001 1/20 0.47
MAPT P10636 2/20 0.45
RAB9A P51151 1/20 0.45
PKM P14618 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10452652 0.98 LTA4H (0.53) LTA4HPLA2G2APTGS2KCNA3MAPT
SCHEMBL24845036 0.87 KCNA3 (0.64) LTA4HPTGS2KCNA3MAPTRAB9A
SCHEMBL4190714 0.82 KDM4E (0.50) LTA4HPTGS2RAB9APKMLMNA
SCHEMBL8671305 0.82 LTA4H (0.75) LTA4HPLA2G2AKCNA3PKMHRH3
SCHEMBL10399922 0.82 DRD4 (0.47) LTA4HPTGS2PKMLMNA
SCHEMBL4499163 0.82 RAB9A (0.51) LTA4HPTGS2MAPTRAB9ATDP1
SCHEMBL10932544 0.81 LTA4H (0.58) LTA4HPLA2G2AKCNA3MAPTRAB9A
SCHEMBL183143 0.79 LTA4H (0.43) LTA4HPTGS2KCNA3MAPTRAB9A
SCHEMBL147539 0.78 LOXL2 (0.52) LTA4HPTGS2RAB9ALMNAHTT
SCHEMBL29610302 0.78 LOXL2 (0.52) LTA4HPTGS2RAB9ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1204413-A2 CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS Bioparken AS (NO) 2002-05-15 EP claimed
EP-1204320-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS Bioparken AS (NO) 2002-05-15 EP claimed
WO-2001007047-A2 CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS BIOPARKEN AS (NO) 2001-02-01 WO claimed
WO-2001006853-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS BIOPARKEN AS (NO) 2001-02-01 WO claimed
EP-0714601-B1 Residual control of parasites by long-acting shampoo formulations VIRBAC (FR) 2000-08-30 EP claimed
EP-0549441-B1 Juvenile hormone agents for systemically treating ectoparasites VIRBAC INC (US) 1997-08-06 EP claimed
EP-0714601-A1 Residual control of parasites by long-acting shampoo formulations LABORATOIRES VIRBAC (FR) 1996-06-05 EP claimed
JP-6211792-A None JP disclosed
JP-59199673-A None JP disclosed
EP-1204413-A2 CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS Bioparken AS (NO) 2002-05-15 EP disclosed
EP-1204320-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS Bioparken AS (NO) 2002-05-15 EP disclosed
WO-2001006853-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS BIOPARKEN AS (NO) 2001-02-01 WO disclosed
WO-2001007047-A2 CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS BIOPARKEN AS (NO) 2001-02-01 WO disclosed
JP-H06211792-A SYSTEMIC CONTROL OF PARASITE VIRBAC SA 1994-08-02 JP disclosed
US-4970222-A INSECTICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-13 US disclosed
US-4879292-A Certain-phenoxy-phenoxy-alkylene-oxy-pyrimidines or symmetrical triazines, thio-analogues thereof, having insecticidal activity SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-07 US disclosed
EP-0128648-B1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP disclosed
US-4751225-A Certain 2-pyridyloxy-lower alkylene-oxy-phenoxy compounds, thio-and methylene analogues having insecticidal properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-14 US disclosed
EP-0128648-A1 Nitrogen-containing heterocyclic compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-19 EP disclosed
JP-S59199673-A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, ITS PREPARATION AND PESTICIDE CONTAINING THE SAME SUMITOMO CHEM CO LTD 1984-11-12 JP disclosed