SCHEMBL754372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27861542	0.84	POLB (0.48)	ALDH1A1LMNAALOX5EPHX2KMT2A
	SCHEMBL7077550	0.83	LMNA (0.51)	ALDH1A1LMNAPRNPRECQLRXFP1
	SCHEMBL24573226	0.82	LMNA (0.48)	ALDH1A1LMNAPRNPRECQLRXFP1
	SCHEMBL7829802	0.81	MAOB (0.45)	ALDH1A1LMNAPRNPRECQLRXFP1
	SCHEMBL7818349	0.77	ERCC5 (0.51)	ALDH1A1LMNAALOX5EPHX2KMT2A
	SCHEMBL4678282	0.76	ALOX5 (0.40)	ALDH1A1LMNAALOX5EPHX2KMT2A
	SCHEMBL4678283	0.76	ALOX5 (0.40)	ALDH1A1LMNAALOX5EPHX2KMT2A
	SCHEMBL756345	0.74	TP53 (0.40)	ALDH1A1LMNAALOX5EPHX2KMT2A
	SCHEMBL756344	0.74	TP53 (0.40)	ALDH1A1LMNAALOX5EPHX2KMT2A
	SCHEMBL14259040	0.73	ABL1 (0.46)	ALDH1A1LMNAPRNPRECQLRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.