Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541819 | 0.95 | ACE (0.41) | GAAMAPTHPGDRAB9AMMP9 | |
| SCHEMBL7547224 | 0.95 | SMN1; SMN2 (0.41) | GAAMAPTHPGDRAB9AMMP9 | |
| SCHEMBL7544077 | 0.95 | MAPK1 (0.42) | GAAMAPTHPGDRAB9AMMP9 | |
| SCHEMBL7544754 | 0.93 | FPR2 (0.49) | RAB9AMMP9RENMMP2MMP3 | |
| SCHEMBL7540684 | 0.93 | GAA (0.42) | GAAMAPTHPGDRAB9AMMP9 | |
| SCHEMBL7546030 | 0.92 | MEN1 (0.42) | MAPTRENMMP2FPR2MAPK1 | |
| SCHEMBL7544683 | 0.90 | MAPT (0.45) | GAAMAPTHPGDRAB9AMMP9 | |
| SCHEMBL7543803 | 0.88 | CTSK (0.43) | GAAMAPTHPGDRAB9AMMP9 | |
| SCHEMBL7544065 | 0.88 | ITGB1 (0.47) | MMP9MMP8MMP2MMP7MMP12 | |
| SCHEMBL7538333 | 0.87 | GAA (0.38) | GAAMAPTHPGDRAB9AMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |