Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559598 | 0.81 | PGR (0.30) | — | |
| SCHEMBL7624027 | 0.81 | SIGMAR1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL7562811 | 0.81 | PGR (0.36) | PTGS1PTGS2 | |
| SCHEMBL7568643 | 0.66 | PGR (0.35) | — | |
| SCHEMBL13221422 | 0.65 | MAPK14 (0.41) | PTGS1PTGS2MAPK14 | |
| SCHEMBL7691782 | 0.64 | CYP2A6 (0.35) | — | |
| SCHEMBL6816479 | 0.63 | PCSK9 (0.34) | — | |
| SCHEMBL9754961 | 0.63 | PTGS1 (0.39) | LPLLIPGPTGS1PTGS2MAPK14 | |
| SCHEMBL10468456 | 0.62 | PTGS1 (0.35) | LPLLIPGPTGS1PTGS2MAPK14 | |
| SCHEMBL11611011 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002543193-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1173426-A1 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | claimed |
| WO-2000066571-A1 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| CN-1131856-C | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PRODUCTS CORP. (US) | 2003-12-24 | — | — | CN | disclosed |
| CN-1349516-A | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |