SCHEMBL7559598

SCHEMBL7559598

CC1(C)C=CCC(c2cc(F)cc(F)c2)=C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7543866 0.81 LPL (0.33)
SCHEMBL7562811 0.77 PGR (0.36) PGR
SCHEMBL7568643 0.73 PGR (0.35) PGR
SCHEMBL7624027 0.70 SIGMAR1 (0.34)
SCHEMBL7540467 0.62
SCHEMBL11611011 0.62
SCHEMBL7691782 0.61 CYP2A6 (0.35) PGR
SCHEMBL7547005 0.60
SCHEMBL6816479 0.60 PCSK9 (0.34)
SCHEMBL19665087 0.58 CA12 (0.50) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1179753-C Contraceptive compositions contaiing antiprogesting and progestinic 2004-12-15 CN claimed
CN-1145618-C Cyclocarbamate derivatives as progesterone receptor modulators �Ʒ� 2004-04-14 CN claimed
EP-1175411-A1 CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS American Home Products Corporation (US) 2002-01-30 EP disclosed
WO-2000066570-A1 CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-09 WO disclosed