Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819843 | 0.83 | SLC9A1 (0.42) | SLC9A1DRD2SLC6A4S1PR5MEN1 | |
| SCHEMBL5758768 | 0.78 | SLC9A1 (0.38) | SLC9A1HTR1ADRD2SLC6A4S1PR5 | |
| SCHEMBL5758774 | 0.78 | SLC9A1 (0.38) | SLC9A1HTR1ADRD2SLC6A4S1PR5 | |
| SCHEMBL5760609 | 0.78 | SLC9A1 (0.38) | SLC9A1HTR1ADRD2SLC6A4S1PR5 | |
| Hydrochloric Acid SCHEMBL7099353 | 0.77 | SLC9A1 (0.38) | SLC9A1HTR1ADRD2SLC6A4S1PR5 | |
| SCHEMBL7866418 | 0.71 | HTR6 (0.40) | SLC9A1HTR1AMEN1KMT2A | |
| SCHEMBL5758016 | 0.68 | L3MBTL1 (0.44) | HTR1AL3MBTL1SLC6A4MEN1KMT2A | |
| SCHEMBL5758789 | 0.66 | HTR2C (0.49) | SLC9A1HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL5760366 | 0.64 | HTR1A (0.41) | HTR1AL3MBTL1SLC6A4 | |
| SCHEMBL5758594 | 0.64 | HTR1A (0.41) | HTR1AL3MBTL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242377-A1 | A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046142-A1 | A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |