Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758768 | 0.85 | SLC9A1 (0.38) | SLC9A1SLC6A4DRD2S1PR5 | |
| SCHEMBL5760609 | 0.85 | SLC9A1 (0.38) | SLC9A1SLC6A4DRD2S1PR5 | |
| SCHEMBL5758774 | 0.85 | SLC9A1 (0.38) | SLC9A1SLC6A4DRD2S1PR5 | |
| SCHEMBL7866418 | 0.85 | HTR6 (0.40) | SLC9A1HTR2CMEN1KMT2AHTR6 | |
| Hydrochloric Acid SCHEMBL7099353 | 0.84 | SLC9A1 (0.38) | SLC9A1SLC6A4DRD2S1PR5 | |
| SCHEMBL7544053 | 0.83 | SLC9A1 (0.39) | SLC9A1MEN1KMT2ASLC6A4DRD2 | |
| SCHEMBL5758789 | 0.81 | HTR2C (0.49) | SLC9A1HTR2CMEN1KMT2ASLC6A4 | |
| SCHEMBL5758016 | 0.80 | L3MBTL1 (0.44) | HTR2CMEN1KMT2AHTR6SLC6A4 | |
| SCHEMBL5762725 | 0.77 | HTR2C (0.51) | HTR2CSLC6A4 | |
| Water SCHEMBL7867947 | 0.77 | HTR1A (0.42) | SLC9A1HTR2CMEN1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |