Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527924 | 0.84 | TDP1 (0.80) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL8232594 | 0.84 | TDP1 (0.59) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL497297 | 0.84 | TDP1 (0.59) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL3635536 | 0.81 | RARA (0.45) | TDP1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL1014744 | 0.79 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL31738422 | 0.79 | TDP1 (0.66) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL395878 | 0.79 | TDP1 (0.66) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL19955179 | 0.79 | TDP1 (0.66) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL31579581 | 0.78 | TSHR (0.46) | ALDH1A1METAP1TSHRTP53DDB1 | |
| SCHEMBL7167731 | 0.77 | TDP1 (0.69) | TDP1ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-213222564-U | Feeding device for DL-p-hydroxyphenylhydantoin | 定陶三化药业有限公司 | 2021-05-18 | — | — | CN | disclosed |
| EP-1210338-A2 | 1,4-DIAZEPINE DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE CENTRAL NERVOUS SYSTEM | IGT Pharma Inc. (CA) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001010846-A2 | 1,4-DIAZEPINE DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE CENTRAL NERVOUS SYSTEM | IGT PHARMA INC. (CA) | 2001-02-15 | — | — | WO | disclosed |