SCHEMBL3635536

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6475331	0.85	KMT2A (0.46)	TDP2TDP1GAAKDM4EALDH1A1
	SCHEMBL7544189	0.81	TDP1 (0.61)	TDP1GAAKDM4EALDH1A1MAPT
	SCHEMBL1624200	0.76	TDP1 (0.62)	TDP1GAAKDM4EALDH1A1POLB
	SCHEMBL8076297	0.73	KIF11 (0.56)	TDP1GAAALDH1A1POLBMAPT
	SCHEMBL873282	0.72	HTT (0.51)	KMOGAAKDM4EALDH1A1POLB
	SCHEMBL19955179	0.72	TDP1 (0.66)	TDP1GAAKDM4EALDH1A1POLB
	SCHEMBL31738422	0.72	TDP1 (0.66)	TDP1GAAKDM4EALDH1A1POLB
	SCHEMBL395878	0.72	TDP1 (0.66)	TDP1GAAKDM4EALDH1A1POLB
	SCHEMBL30066684	0.72	KMO (0.72)	RARARARBRARGTRIM24TRIM33
	SCHEMBL16166011	0.72	KMO (0.72)	RARARARBRARGTRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.