Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.65 |
| ▸ | CTSL | P07711 | 10/20 | 0.65 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28723295 | 0.93 | CTSL (0.62) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL4828679 | 0.93 | CTSL (0.62) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL11685409 | 0.90 | CTSL (0.56) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL8387978 | 0.89 | FOLH1 (0.65) | CTSSCTSLCTSKFOLH1SIRT2 | |
| SCHEMBL10421088 | 0.89 | FOLH1 (0.62) | CTSSCTSLCTSKTACR1FOLH1 | |
| SCHEMBL7515531 | 0.85 | FOLH1 (0.58) | CTSSCTSLCTSKTACR1FOLH1 | |
| SCHEMBL6841663 | 0.85 | FOLH1 (0.58) | CTSSCTSLCTSKTACR1FOLH1 | |
| SCHEMBL6560575 | 0.85 | CTSS (0.64) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL6560581 | 0.85 | CTSS (0.64) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL19520868 | 0.84 | FOLH1 (0.57) | CTSSCTSLCTSKTACR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002047263-A | 2-AMINO-OMEGE-CYANOALKANOIC ACID DERIVATIVE AND METHOD OF PRODUCING THE SAME | SUMIKA FINE CHEMICALS CO LTD | 2002-02-12 | — | — | JP | disclosed |