Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 8/20 | 0.53 |
| ▸ | CTSK | P43235 | 7/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541415 | 0.91 | KLK5 (0.54) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL7896684 | 0.90 | KLK5 (0.67) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL20415892 | 0.88 | KLK5 (0.56) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL28205403 | 0.88 | KLK5 (0.56) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL9078917 | 0.88 | KLK5 (0.58) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL9078913 | 0.88 | KLK5 (0.58) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL6292728 | 0.87 | KLK5 (0.72) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL1196457 | 0.87 | KLK5 (0.72) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL21473748 | 0.87 | KLK5 (0.72) | KLK5CTSSCTSKACECTSB | |
| SCHEMBL84524 | 0.87 | KLK5 (0.72) | KLK5CTSSCTSKACECTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1376143-A | Carboxylic acid derivatives and adhesion molecule inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2002-10-23 | — | — | CN | disclosed |
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |