Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586301 | 0.90 | MAPT (0.56) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7588285 | 0.89 | MAPT (0.45) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7536935 | 0.84 | CTSB (0.49) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6183250 | 0.80 | MAPT (0.44) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6182191 | 0.78 | MAPT (0.55) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6183082 | 0.77 | CTSS (0.46) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6183359 | 0.76 | ENPP2 (0.46) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7586450 | 0.76 | GPR119 (0.41) | — | |
| SCHEMBL6182283 | 0.75 | CTSB (0.44) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6183637 | 0.74 | PARP1 (0.51) | MAPTLMNASMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |