SCHEMBL7545112

SCHEMBL7545112

COc1ccc(Sc2ccc(OC)cc2C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.48
HTR3A P46098 3/20 0.48
IDO1 P14902 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
PTGIR P43119 2/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA12 O43570 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ACHE P22303 1/20 0.41
HAO1 Q9UJM8 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP12 P39900 2/20 0.40
HSD17B10 Q99714 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10756090 0.88 ALDH1A1 (0.44) HTR3AMEN1POLBKMT2ACA1
SCHEMBL23999244 0.83 ALDH1A1 (0.50) HTR1AHTR3AIDO1MEN1POLB
SCHEMBL20591216 0.81 MEN1 (0.55) HTR1AHTR3AMEN1POLBKMT2A
SCHEMBL12313604 0.79 ALDH1A1 (0.44) HTR3AMEN1POLBKMT2ACA1
SCHEMBL5316082 0.78 HTR1A (0.52) HTR1AHTR3AIDO1MEN1POLB
SCHEMBL8736422 0.78 ACHE (0.48) HTR1AHTR3AIDO1MEN1POLB
SCHEMBL3640883 0.78 ALDH1A1 (0.61) HTR3AMEN1POLBKMT2ACA1
SCHEMBL482369 0.76 CA1 (0.65) MEN1POLBKMT2APTGIRCA1
SCHEMBL30548759 0.75 MEN1 (0.62) HTR1AHTR3AIDO1MEN1POLB
SCHEMBL3547996 0.75 HTR1A (0.53) HTR1AHTR3AIDO1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0729069-B1 Benzanthrone polymerization gate in photopolymerizable composition KODAK POLYCHROME GRAPHICS CO (US) 2002-05-15 EP disclosed
EP-0859283-B1 4-(Alkoxyhydroxy)styryl triazine photoinitiators KODAK POLYCHROME GRAPHICS CO (US) 2000-11-02 EP disclosed
US-5900345-A Surfactant in precoat for lithographic plates KODAK POLYCHROME GRAPHICS, LLC (US) 1999-05-04 US disclosed
EP-0575802-B1 Photopolymeric printing plates KODAK POLYCHROME GRAPHICS CO (US) 1999-02-24 EP disclosed
US-5837586-A LITHOGRAPHIC PRINTING PLATES RESISTANT TO SURFACE BLOOMING KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 1998-11-17 US disclosed
EP-0859283-A1 4-(Alkoxyhydroxy)styryl triazine photoinitiators INTERNATIONAL PAPER COMPANY (US) 1998-08-19 EP disclosed
EP-0729069-A1 Benzanthrone polymerization gate in photopolymerizable composition INTERNATIONAL PAPER COMPANY (US) 1996-08-28 EP disclosed
US-5543262-A PHOTOLITHOGRAPHY USING A BENZANTHRONE TO INHIBIT POLYMERIZATION BELOW A THRESHOLD AMOUNT OF ACTINIC RADIATION BUT PERMITS IT WHEN ABOVE; ANTISOILANTS; BACKGROUND; QUALITY REPRODUCITN; ANTIHALATION AGENTS; HOTSPOTS INTERNATIONAL PAPER COMPANY (US) 1996-08-06 US disclosed
US-5286594-A Nontacky, mar resistant, easily developed durable plates INTERNATIONAL PAPER COMPANY (US) 1994-02-15 US disclosed
EP-0575802-A1 Photopolymeric printing plates INTERNATIONAL PAPER COMPANY (US) 1993-12-29 EP disclosed
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP disclosed
EP-0106156-B1 LIGHT-SENSITIVE COMPOSITION HOECHST CELANESE CORPORATION (US) 1988-12-21 EP disclosed
EP-0212482-A2 Process for obtaining negative images from positive photoresists HOECHST CELANESE CORPORATION (US) 1987-03-04 EP disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 EP disclosed
EP-0089509-B1 METHOD FOR THE ELECTROPHORETIC DEPOSITION OF RADIATION-SENSITIVE COATINGS ON METALLIC BASES, AND USE OF THE COATED MATERIAL AS AN OFFSET PRINTING PLATE AMERICAN HOECHST CORPORATION (US) 1986-05-28 EP disclosed
EP-0106156-A2 Light-sensitive composition HOECHST CELANESE CORPORATION (US) 1984-04-25 EP disclosed
EP-0089509-A1 Method for the electrophoretic deposition of radiation-sensitive coatings on metallic bases, and use of the coated material as an offset printing plate AMERICAN HOECHST CORPORATION (US) 1983-09-28 EP disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 EP disclosed
US-4021243-A Diazo light-sensitive copying composition and process of using in the manufacture of screen printing stencils HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-03 US disclosed