SCHEMBL755319

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756220	0.91	JAK2 (0.43)	JAK2JAK3ELOVL1GRM5GRM3
	SCHEMBL754587	0.89	JAK2 (0.41)	JAK2JAK3ELOVL1GRM5GRM3
	SCHEMBL751416	0.88	JAK2 (0.44)	JAK2JAK3KMT2AELOVL1GRM5
	SCHEMBL753011	0.87	JAK2 (0.45)	JAK2JAK3ELOVL1GRM5GRM3
	SCHEMBL753218	0.86	JAK2 (0.44)	JAK2JAK3ELOVL1GRM5GRM3
	SCHEMBL751248	0.83	LMNA (0.44)	JAK2JAK3KMT2AMAOAMAOB
	SCHEMBL754532	0.82	JAK2 (0.43)	JAK2JAK3ELOVL1GRM5GRM3
	SCHEMBL2487611	0.76	JAK2 (0.46)	JAK2JAK3ELOVL1GRM5MAOA
	SCHEMBL755973	0.76	PKM (0.41)	JAK2JAK3GRM5GRM3LIPG
	SCHEMBL755768	0.75	LIPG (0.34)	KMT2ALIPGTDP1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.