SCHEMBL754535

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13005381	0.80	LTA4H (0.52)	LTA4HHTTLMNAALDH1A1SMN1; SMN2
	SCHEMBL20176875	0.80	LTA4H (0.39)	LTA4HHTTLMNASMN1; SMN2CYP11B1
	SCHEMBL20176877	0.79	LMNA (0.60)	LTA4HHTTLMNAALDH1A1SMN1; SMN2
	SCHEMBL755812	0.78	MEN1 (0.46)	LTA4HHTTALDH1A1L3MBTL1
	SCHEMBL4796162	0.78	TEAD4 (0.59)	TSHRMAOAALDH1A1SMN1; SMN2TDP1
	SCHEMBL509776	0.78	LTA4H (0.50)	LTA4HTSHRHTTLMNANR1H2
	SCHEMBL4796155	0.78	TEAD4 (0.34)	LTA4HTSHRHTTALDH1A1SMN1; SMN2
	SCHEMBL19408509	0.77	LTA4H (0.55)	LTA4HTSHRHTTNR1H2BAX
	SCHEMBL16344897	0.77	LTA4H (0.55)	LTA4HTSHRHTTNR1H2BAX
	Dimethylamine SCHEMBL2599651	0.75	LTA4H (0.46)	LTA4HTSHRHTTNR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.