SCHEMBL754535

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20176875	0.80	LTA4H (0.39)	LTA4HHTTLMNASMN1; SMN2CYP11B1
	SCHEMBL13005381	0.80	LTA4H (0.52)	LTA4HHTTLMNAALDH1A1SMN1; SMN2
	SCHEMBL20176877	0.79	LMNA (0.60)	LTA4HHTTLMNAALDH1A1SMN1; SMN2
	SCHEMBL4796155	0.78	TEAD4 (0.34)	LTA4HTSHRHTTALDH1A1SMN1; SMN2
	SCHEMBL4796162	0.78	TEAD4 (0.59)	TSHRMAOAALDH1A1SMN1; SMN2TDP1
	SCHEMBL509776	0.78	LTA4H (0.50)	LTA4HTSHRHTTLMNANR1H2
	SCHEMBL755812	0.78	MEN1 (0.46)	LTA4HHTTALDH1A1L3MBTL1
	SCHEMBL19408509	0.77	LTA4H (0.55)	LTA4HTSHRHTTNR1H2BAX
	SCHEMBL16344897	0.77	LTA4H (0.55)	LTA4HTSHRHTTNR1H2BAX
	SCHEMBL20176869	0.75	DRD1 (0.45)	LTA4HTSHRHTTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.