Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755706 | 0.83 | MMP3 (0.41) | CXCR4KMT2AMEN1TP53POLB | |
| SCHEMBL753758 | 0.80 | MMP3 (0.38) | TP53POLB | |
| SCHEMBL755446 | 0.79 | TEAD4 (0.42) | MAPTKMT2APOLBTDP1L3MBTL1 | |
| SCHEMBL754737 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1TP53POLB | |
| SCHEMBL753088 | 0.77 | POLB (0.38) | MAPTPOLBTDP1L3MBTL1 | |
| Dimethylamine SCHEMBL752802 | 0.77 | CNR2 (0.38) | MAPTPOLBTDP1 | |
| SCHEMBL752233 | 0.77 | MAPT (0.48) | MAPTKMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL751255 | 0.76 | KMT2A (0.38) | KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL751254 | 0.76 | HPGD (0.50) | MAPTKMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL751551 | 0.76 | GAA (0.38) | KMT2AMEN1SMN1; SMN2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-2181985-B1 | Antiviral Agent | SHIONOGI & CO (JP) | 2011-10-26 | — | — | EP | disclosed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | disclosed |