SCHEMBL75458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22789979	1.00	LMNA (0.41)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL15339882	0.79	LMNA (0.45)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL120085	0.76	ALDH1A1 (0.41)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL13409254	0.76	ALDH1A1 (0.41)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL3365931	0.75	LMNA (0.47)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL11908671	0.74	LMNA (0.46)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL20375290	0.74	LMNA (0.46)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL28630522	0.74	LMNA (0.46)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL947840	0.74	LMNA (0.46)	LMNAKDM4EHSD17B10ALDH1A1KMT2A
	SCHEMBL13867048	0.73	KDM4E (0.40)	LMNAKDM4EHSD17B10ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.