Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120085 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL3881811 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL75458 | 0.76 | LMNA (0.41) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL22789979 | 0.76 | LMNA (0.41) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL3877540 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL3871321 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL13867048 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL3873295 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL15339882 | 0.72 | LMNA (0.45) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL9908400 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS LLC (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS LLC (US) | 2010-04-22 | — | — | US | disclosed |
| WO-2009061723-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | PROMERUS, LLC (US) | 2009-05-14 | — | — | WO | disclosed |
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | PROMERUS, LLC (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | PROMERUS, LLC (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118539-A1 | forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization | MMAB, ADH1C, OXER1 | ALDH1A1 50/4885KDM4E 3566/4885HSD17B10 1279/4885 |
| US-20100099906-A1 | GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES | GNE, GALE, EXOSC5 | ALDH1A1 230/4885KDM4E 2962/4885HSD17B10 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.