Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL7081803 | 0.85 | ALDH1A1 (0.54) | TSHRAKT1POLBMAPTALDH1A1 | |
| SCHEMBL27500000 | 0.83 | SMN1; SMN2 (0.46) | TSHRPOLBKMT2AMAPTALDH1A1 | |
| SCHEMBL27756382 | 0.81 | TSHR (0.41) | TSHRMAPTALDH1A1KDM4ETDP1 | |
| Biphenyl SCHEMBL3991647 | 0.81 | POLB (0.47) | TSHRPOLBKMT2AMAPTALDH1A1 | |
| Glycine SCHEMBL27463277 | 0.81 | HDAC1 (0.47) | TSHRPOLBKMT2AMAPTALDH1A1 | |
| Phenol SCHEMBL27480309 | 0.79 | ESRRB (0.49) | TSHRAKT1POLBESRRBALDH1A1 | |
| Toluene SCHEMBL27945492 | 0.79 | POLB (0.46) | TSHRAKT1POLBKMT2AALDH1A1 | |
| Benzene SCHEMBL28161453 | 0.78 | LMNA (0.54) | TSHRAKT1POLBKMT2AMAPT | |
| Chlorobenzene SCHEMBL27773693 | 0.78 | POLB (0.44) | TSHRAKT1POLBKMT2AMAPT | |
| Phenol SCHEMBL28008035 | 0.78 | ESRRB (0.47) | TSHRAKT1POLBESRRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |