Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754616 | 1.00 | RAB9A (0.34) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL2486924 | 0.89 | RAB9A (0.38) | RAB9ALMNAMAPTALDH1A1RXFP1 | |
| SCHEMBL2486923 | 0.89 | RAB9A (0.38) | RAB9ALMNAMAPTALDH1A1RXFP1 | |
| SCHEMBL17922045 | 0.80 | RAB9A (0.36) | RAB9A | |
| SCHEMBL756872 | 0.73 | POLB (0.37) | RAB9ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL2958453 | 0.61 | LMNA (0.64) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL8496249 | 0.61 | ALDH1A1 (0.43) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21222589 | 0.60 | CES2 (0.58) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL755130 | 0.59 | ALDH1A1 (0.34) | RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL836180 | 0.58 | CES2 (0.62) | RAB9ALMNAMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |
| CN-101513402-B | Antiviral agent | SHIONOGI & CO | 2012-03-21 | — | — | CN | disclosed |