SCHEMBL756872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752052	0.88	POLB (0.39)	POLBALDH1A1PARP1LMNATSHR
	SCHEMBL755130	0.83	ALDH1A1 (0.34)	POLBALDH1A1RAB9APARP1LMNA
	SCHEMBL753319	0.81	ALDH1A1 (0.39)	POLBALDH1A1RAB9ALMNATSHR
	SCHEMBL2486924	0.77	RAB9A (0.38)	POLBALDH1A1RAB9APARP1LMNA
	SCHEMBL2486923	0.77	RAB9A (0.38)	POLBALDH1A1RAB9APARP1LMNA
	SCHEMBL756448	0.77	LIPG (0.42)	POLBALDH1A1LMNATSHRNPSR1
	SCHEMBL2513404	0.77	POLB (0.42)	POLBALDH1A1LMNATSHRCYP1A2
	SCHEMBL752898	0.76	POLB (0.37)	POLBALDH1A1LMNATSHRCYP1A2
	SCHEMBL754653	0.75	MAPT (0.41)	POLBALDH1A1LMNATSHRMAPT
	SCHEMBL755129	0.74	ALDH1A1 (0.34)	POLBALDH1A1LMNATSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.