Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934594 | 0.77 | ESR2 (0.44) | CYP2C9MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL19454269 | 0.76 | MAOA (0.48) | CYP2C9MAOAMAOBATM | |
| SCHEMBL16046136 | 0.74 | MAPT (0.41) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL4323808 | 0.72 | MEN1 (0.40) | CYP2C9LMNAMAPTMEN1KMT2A | |
| SCHEMBL40368 | 0.70 | CYP2C9 (0.55) | CYP2C9LMNAMAPTMEN1KMT2A | |
| SCHEMBL2011512 | 0.69 | MAPT (0.35) | CYP2C9LMNAMAPTMEN1KMT2A | |
| SCHEMBL1387828 | 0.68 | CFTR (0.38) | CYP2C9LMNAMAPTCFTRGOPC | |
| SCHEMBL4583348 | 0.67 | LMNA (0.46) | CYP2C9LMNAMAPTMEN1KMT2A | |
| SCHEMBL29040549 | 0.67 | PTPN1 (0.36) | CYP2C9LMNACFTRGOPCGAA | |
| SCHEMBL6241456 | 0.66 | CYP2C9 (0.42) | CYP2C9LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873122-B1 | USE OF 3,4-DIPHENYL CHROMANS FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PROPHYLAXIS OF PROSTATIC CARCINOMA | NOVO NORDISK AS (DK) | 2002-06-12 | — | — | EP | disclosed |
| EP-0873122-A1 | USE OF 3,4-DIPHENYL CHROMANS FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PROPHYLAXIS OF PROSTATIC CARCINOMA | NOVO NORDISK A/S (DK) | 1998-10-28 | — | — | EP | disclosed |